Bury v Stockport
Striker Glynn Hurst will hope to be handed a start if Bury boss Alan Knill opts to rotate his side after seven league matches unchanged.
Defender Ryan Cresswell and midfielder Richie Baker could replace Efe Sodje and Elliott Bennett respectively.
Stockport skipper Gareth Owen could again be left out after a dispute with manager Jim Gannon. Matty McNeil (calf) is Gannon's only injury absentee.
Chester v Morecambe
Kevin Roberts is available for Chester after a one-match ban, while Anthony Barry and Jay Harris could be handed rare places in the starting line-up.
Morecambe defender Danny Adams (virus) looks set to join Paul Lloyd (ankle), Matt Blinkhorn (cartilage) and Michael Howard (back) on the sidelines.
Diarmuid O'Carroll should retain his place while Neil Wainwright and Aaron Taylor will battle for a midfield spot.
Darlington v Huddersfield
Former Huddersfield striker Pawel Abbott (ankle) will miss out on a reunion with his former club.
Keeper Przemyslaw Kazimierczak and midfielder David Poole could replace Simon Brown and Ricky Ravenhill.
The Terriers will be without midfielder Ian Craney (hamstring) and veteran striker Andy Booth (back), but on-loan Liam Dickinson has been cleared to play by parent club Derby.
Rochdale v Carlisle
Dale will be without defender Simon Ramsden (calf), while striker Jon Shaw and midfielder Mark Jones remain sidelined by hamstring problems.
Striker Kallum Higginbotham is a doubt after missing Saturday's defeat to Dagenham with a badly bruised foot.
Carlisle skipper Paul Thirlwell serves a ban, while Michael Bridges and Jennison Myrie-Williams could replace strikers Scott Dobie and Danny Carlton.
Scunthorpe v Grimsby
The Iron's Joe Murphy, Grant McCann and Krystian Pearce are on international duty, with Murphy also suspended.
Josh Lillis fills in for him while Garry Thompson and Kevan Hurst are doubts with tendonitis and Michael Lea (rib) and Kenny Milne (knee) miss out.
Malvin Kamara is ineligible for Grimsby but fellow loanee Tomi Ameobi has been cleared to play. Paul Bolland (knee) and Richard Hope (groin) are absent.
Brighton v Leyton Orient
Adam Virgo and Joe Anyinsah could form a makeshift Brighton strikeforce as Nicky Forster (knee) and weekend hat- trick ace Glenn Murray (thigh) sit out.
Steve Thomson may not be risked after two games out with illness.
Tamika Mkandawire is battling to make his Orient return after a groin injury, but Danny Granville (hernia), Wayne Gray and Loick Pires (both knee) miss out and Dean Morgan (foot) is a doubt.
Cheltenham v Walsall
Scott Murray (leg) joins David Bird (toe), Shane Duff (Achilles) and John Finnigan (heel) on Town's injury list.
Josh Payne and Barry Hayles are banned and loanees Drissa Diallo and James Wesolowski are both cup-tied.
Rene Gilmartin replaces Saddlers keeper Clayton Ince (international duty). Mark Bradley and Sofiene Zaaboub are doubts and Rhys Weston and Netan Sansara complete three-match bans.
Gillingham v Colchester
Gillingham are without Andrew Crofts (international duty), Mark McCammon (ban) and injured trio Gary Mulligan, Dennis Oli and Adam Miller.
Luis Cumbers (tonsillitis) is a doubt, with Nicky Southall, Alan Julian and Leigh Mills all set to start.
The Us' Chris Coyne (Australia) and Medy Elito (England U19) are on international duty, while tendonitis keeps Matt Lockwood on the sidelines.
Hereford v Swindon
Nick Chadwick, Clint Easton and Dean Beckwith are expected to feature in a much-changed Hereford line-up.
Craig Samson is set to replace keeper Darren Randolph (knee) while Ben Smith, Steve Guinan, Sam Oji and Robbie Threlfall all miss out.
Hasney Aljofree (viral infection) and Jamie Vincent (knee) remain sidelined for Swindon, who should be unchanged from Friday's draw with Hartlepool.
Luton v Brentford
Garreth O'Connor looks set to come straight into the Luton line-up in place of defender Harry Worley.
Kevin Watson should be fit enough for a place on the bench, leaving Drew Talbot (knee) as Town's only absentee.
Brett Johnson (groin) and Gary Smith (hernia) miss out for Brentford, while Kevin O'Connor and Marvin Williams could start after being named among the substitutes at the weekend.
MK Dons v Bournemouth
Luke Chadwick is likely to be omitted for holders MK Dons, but Carl Regan could return to the starting XI.
Aaron Wilbraham (ankle) and Danny Swailes (Achilles) miss out but keeper Willy Gueret should be available.
Bournemouth defender Jason Pearce is expected to be fit despite going off with a head wound in the defeat at Wycombe, but Alan Connell (knee) will be out for several more weeks.
P'borough v Dag & Red
Joe Lewis and Craig Morgan could feature for Posh before joining up with England U21 and Wales respectively but Gabriel Zakuani is away with DR Congo.
Dean Keates, Sergio Torres (both knee), Shane Blackett (shoulder), Aaron Mclean (elbow) and Paul Coutts (foot) sit out.
Dagenham could recall Jon Nurse for Danny Foster, while Mark Arber should retain his place and Shane Huke could earn a first start this season.
Wycombe v Shrewsbury
Wycombe boss Peter Taylor is likely to rest teenage winger Matty Phillips, with Gavin Grant coming in.
Lewis Hunt (groin), Will Antwi (toe) and Gary Holt (hernia) miss out but Nathan Ashton is fit and Scott McGleish will hope to step into the starting XI.
Richard Walker could step up to the Shrews' starting XI, while Michael Symes (knee) could also feature and Michael Jackson (head) is fit to play.