Bristol R v Leyton Orient
Bristol Rovers defender Steve Elliott is hoping to be passed fit after suffering a dead leg against Crewe.
Joe Jacobson is on international duty with Wales U21s and Ryan Green is still struggling with a hamstring problem.
Leyton Orient boss Martin Ling welcomes back JJ Melligan and Glenn Morris should also return. Dean Morgan remains doubtful with a foot injury along with Tamika Mkandawire and Danny Granville.
Cheltenham v Colchester
Cheltenham boss Martin Allen is set to recall the likes of Alan Wright, Alex Russell and Darren Kenton after the midweek Johnstone's Paint Trophy clash.
On-loan duo Drissa Diallo and James Wesolowski will also come into contention having been ineligible for the match against Walsall.
Colchester are still without Matt Lockwood (tendinitis), Chris Coyne and Medy Elito (both international duty).
Leeds v Brighton
Leeds defender Alan Sheehan has suffered a recurrence of his hamstring injury so Aidan White or Ben Parker could be brought in as cover.
Jermaine Beckford, Luciano Becchio, Jonathan Douglas, Fabian Delph, Frazer Richardson and Paul Telfer are all back in contention.
Glenn Murray (thigh) remains an injury doubt for Brighton, while Nicky Forster (knee) has been ruled out for a month.
MK Dons v Carlisle
MK Dons manager Roberto Di Matteo will be without Canada international Ali Gerba so Kevin Gallen is set to partner Sam Baldock in attack.
Flavien Belson begins a three-match ban and winger Craig Dobson is out with a stress fracture to his left leg.
Paul Thirlwell (calf) will be absent for Carlisle but John Ward's side are boosted by the signing of Graham Kavanagh, who is available to play.
Scunthorpe v Crewe
Joe Murphy is back from suspension and should return to Scunthorpe's starting line-up in place of Josh Lillis.
Grant McCann and Krystian Pearce are on international duty so Ian Morris and David Mirfin will keep their places.
Crewe have major doubts over Julien Baudet (hamstring). Dennis Lawrence is away on international duty, while George Abbey and Chris McCready (both hamstring) remain on the sidelines.
Southend v Stockport
Southend striker Dougie Freedman is out with a thigh injury and goalkeeper Steve Mildenhall is still two weeks away from a return.
Stockport are boosted by the arrival of Tony Kane and Jaroslaw Fojut but are missing Owain fon Williams and Peter Thompson (both international duty).
Anthony Pilkington and Stephen Gleeson will be available and Jason Taylor is also in contention.
Swindon v Huddersfield
Swindon boss Maurice Malpas is expected to name an unchanged line-up despite Barry Corr pushing hard for a recall.
Hasney Aljofree (virus) is unlikely to feature meaning Jerel Ifil should continue in defence. Jamie Vincent (knee) is targeting a November return.
Huddersfield are without injured pair Ian Craney (hamstring) and Andy Booth (back) but Gary Roberts is available after winning his red card appeal.
Tranmere v Millwall
Ian Goodison and Ed Sonko (both international duty) will be absent for Tranmere so Godwin Antwi and Chris Shuker are set to replace them.
Tresor Kandol returns for Millwall after completing a three-match ban but Jermaine Easter still has two games of his suspension remaining.
Nadjim Abdou will have a late fitness check on a slight groin strain but is expected to be passed fit.
Walsall v Peterborough
Rene Gilmartin will start in goal for Walsall again in the absence of Clayton Ince, who is on international duty.
Rhys Weston and Netan Sansara both return after completing their three-match bans, but Sofiene Zaaboub (groin) looks doubtful.
Peterborough have a defensive crisis as Craig Morgan and Gabriel Zakuani are both on international duty while Chris Westwood is out with a calf problem.